Ion channel mutations in AF: Signal or noise?
نویسندگان
چکیده
منابع مشابه
Neurological diseases caused by ion-channel mutations.
During the past decade, mutations in several ion-channel genes have been shown to cause inherited neurological diseases. This is not surprising given the large number of different ion channels and their prominent role in signal processing. Biophysical studies of mutant ion channels in vitro allow detailed investigations of the basic mechanism underlying these 'channelopathies'. A full understan...
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Several neurological diseases-including neuromuscular disorders, movement disorders, migraine, and epilepsy-are caused by inherited mutations of ion channels. The list of these "channelopathies" is expanding rapidly, as is the phenotypic range associated with each channel. At present the best understood channelopathies are those that affect muscle-fibre excitability. These channelopathies produ...
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2008
ISSN: 1547-5271
DOI: 10.1016/j.hrthm.2008.01.014